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Fasinex 240 – the cream of liver fluke control...

  • Recommended for dairy cows during the dry period.
  • Contains triclabendazole, the only flukicide to kill all 3 stages of liver fluke: adult, immature and early immature.
  • Offering outstanding productivity benefits including improved yields, more milk solids and up to a 47% improvement in calving rates1.

Easy to use

  • Concentrated, low volume drench.
  • Easy to administer: 1 ‘hit’ dose.
  • A single oral dose, given during the dry period when high numbers of early immature liver fluke are likely to be present, removes all 3 stages of liver fluke when dairy cows will benefit most.

Protecting the Irish dairy herd

The Irish dairy sector exports 4.5 million tonnes of product with a value of 2.2 billion per annum2. Ireland’s climate and soil favour the life cycle of the liver fluke parasite (Fasciola hepatica) and its intermediate host the mud snail (Galba truncatula). Consequently Irish livestock are subject to some of the highest liver fluke infection levels in the world.

The objective of liver fluke control is to minimise infection, and keep it at a level that does not impair cattle welfare or affect the efficiency or economics of production.

Effect of liver fluke in dairy cows

Liver fluke has 3 stages – early immature, immature and adult – all of which cause liver damage. The earlier you kill liver fluke in dairy cows the better.

By killing early immature liver fluke, FASINEX 240 stops further liver damage caused by the immature and adult stage liver fluke from ever occurring.Liver condemnations at slaughter or acute liver fluke disease are obvious losses. However, subclinical disease is far more important resulting in reduced:

Milk yield and quality

  • Milk yield losses of up to 1 kg per day over a 305 day lactation5
  • Reduced milk butterfat concentration6


  • Reduced conception rates in heifers by 50%1
  • First oestrus in dairy heifers delayed by 39 days7

Growth rates

  • Reduced live weight gain in younger animals by up to 1.2 kg per week5

Liver fluke life cycle

Liver Fluke has a complex lifecycle with a main host (Cattle and sheep) and an intermediate host (the mud snail).

Inside cattle

Outside the animal: on pasture and in mud snails

Liver fluke kill

Liver fluke control

Testing and management

To be able to treat and manage this complex problem effectively – and limit its detrimental effects on dairy cow performance, health and welfare – it is vital to know the status of your herd.

Effective treatment

Some products leave the early immature and immature stages alive. Only triclabendazole, in FASINEX 240, kills all 3 stages of liver fluke, reducing liver damage and pasture contamination.

effective treatement

The benefit of killing all 3 stages of liver fluke

Killing all 3 stages of liver fluke means less liver damage, less blood loss, better growth and productivity.

A study comparing live weight gain of animals treated for all 3 stages of liver fluke, compared to animals treated for adult liver fluke only, demonstrated a benefit of 8 kg over a 20 week period9.

Because it kills liver fluke at earlier development stages, Fasinex 240 achieves the same level of liver fluke kill with fewer doses than oxyclozanide or albendazole. This could save you time and money, improving productivity and reducing the need to handle cattle to eliminate the remaining liver flukes.

benefits of fasinex

For dairy cows in the dry period

Fasinex 240 is the ideal liver fluke treatment for dairy cows producing milk for human consumption.

How much Fasinex 240 will I need?

12mg triclabendazole/kg bodyweight.
i.e. 5ml FASINEX 240 per 100kg bodyweight.
dry period

Fasinex 240, 24 % w/v oral suspension for cattle.


A cream coloured oral suspension for cattle containing 240 mg triclabendazole.


For the treatment of acute, subacute and chronic infection due to early immature, immature, and mature stages of Fasciola hepatica. If infected animals are treated before disease has developed, fasciolosis can be prevented.

Dosage and administration

To ensure administration of a correct dose, bodyweight should be determined as accurately as possible; accuracy of the dosing device should be checked. If animals are to be treated collectively rather than individually they should be grouped according to their bodyweight and dosed accordingly, in order to avoid under- or over-dosing. Administer 5 ml/100 kg bodyweight, equivalent to 12 mg triclabendazole per kg of bodyweight. FASINEX is administered orally after thorough shaking of the suspension. Most types of automatic drenching guns are suitable.

Clean drenching gun before and after use. FASINEX can safely be given to young, pregnant or stressed cattle. However, the product is not permitted for use in lactating animals producing milk for human consumption. Fasinex 240 is given once. The administration may be repeated several weeks or months after the first treatment depending on the epidemiological situation. In case of acute fasciolosis, treat immediately, and repeat on the advice of the prescriber, depending on the ongoing level of challenge.

Dosing Programme:

Areas of heavy liver fluke infection:

On land where sheep are being treated according to the preventative programme and where cattle are also grazing these areas, Fasinex 240 should be administered to the cattle on the same treatment dates as the sheep. Treatment times should be customised under veterinary advice for each individual farm. Spring/summer treatments prevent the liver flukes entering the mud snail and so the life cycle is broken. Every animal on the same land including sheep should be included in the programme and all animals should be treated on the same day. Fasinex 5% should be used in sheep. All bought in animals should be dosed before joining the main herd.

Areas of Average Liver fluke Infection:
Outwintered cattle:

Dose all cattle exposed to liver fluke infected pastures at regular intervals of 8 -10 weeks throughout the liver fluke season.

Housed cattle:

Dose cattle, which have grazed liver fluke infected pasture in the Autumn and at the time of or shortly after housing. Dosing should start at the beginning of the liver fluke season when animals are still outdoors.

Bought in cattle:

Dose before joining the main herd.

Treatment of acute outbreaks:

The herd should be treated immediately after diagnosis and veterinary advice should be sought for subsequent dosing intervals.

Contraindications, Warnings, etc.

Do not eat, drink, or smoke while handling the product. Wash hands and exposed skin after handling the product. Wash splashes from eyes and skin immediately with water. Remove contaminated clothing. Clean drenching equipment before and after use.

Keep out of the reach and sight of children.

Withdrawal Periods

Meat and offal: 56 days.
Milk: Milk for human consumption may only be taken from 48 hours after calving. If calving occurs before 35 days after treatment, milk for human consumption may only be taken after 35 days plus 48 hours after the treatment.
Use during pregnancy and lactation:

FASINEX is safe for use in all stages of pregnancy and lactation. However, the product is not permitted for use in lactating animals producing milk for human consumption.

Not intended for use within 35 days of calving. Do not use in animals with a known hypersensitivity to the active ingredient. Do not administer Fasinex 240 to sheep.

Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy.

Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used.

Any unused veterinary medicinal product or waste material derived from such veterinary medicinal products should be disposed of in accordance with national requirements. Do not contaminate ponds, waterways or ditches with the product or used container.

Pharmaceutical Precautions

Shake the container before use. Once opened, use within 12 months. Store in tightly closed original container.

Marketing Authorisation Number

VPA 10825/004/002

For further information about Fasinex 240 contact:
Elanco Animal Health, Lilly House, Priestley Road, Basingstoke, Hampshire, RG24 9NL.
Tel +44 (0)1256 353131 or in Ireland Tel 051 377201.
Fasinex® 240 contains 24% w/v triclabendazole LM.
Fasinex® 240 is a registered trade mark owned by or licensed to Eli Lilly and Company, its affiliates or subsidiaries. Advice on the use of this or alternative medicines must be sought from the medicine prescriber.

Legal category:

Licensed Merchant. IEDRYFAS00001 rdp19903/06/15
Use medicines responsibly
1. Oakley G.A, et al 1979, Veterinary Record, 104, 503 - 507.
2. Moorepark dairy levy research update, 4/5/2011, Kilkenny Greenfield dairy programme.
3. Irish Veterinary Journal Volume 63, Number 11, pg 702.
4. DeLiver project www.deliver-project.eu.
5. University of Reading, Department of Agriculture and Food Economics, The Economics of Fascioliasis (Liver Fluke).
6.Department of Agriculture and Rural Development, Technical Note, Dairy, 13th April 2003.
7. M.C Lopez – Diaz et al, Theriogenology, 1998.
8. Boray J.C, Chemotherapy of fascioliasis (Research done by Ciba-Geigy Inc).
9.Boray, JC, NSW, Veterinary Proceedings, Vol 18, 1982.
* Boray JC, NSW Veterinary Proceedings, Vol 18, 1982.
# Claims based on published summary of product characteristics for products containing the active ingredients specified. Information accurate on the date of publication of this detailer, September 2012.